Job Description
General summary:
Vertex is seeking a talented scientist to join our small molecules Analytical Development group in Abingdon, UK. This individual will play a central role in advancing transformative medicines by leading analytical chemistry activities for small molecule development programs from preclinical through to Phase 1. This role includes representing Analytical Development at cross-functional project team meetings, and demonstrable experience to resolve project challenges in collaboration with other R&D functions is required. The ability to work both independently and in a matrix team environment is essential to succeed in this position.
Key Duties and Responsibilities:
* Project oversight: represent Analytical Development at cross-functional teams and effectively communicate issues and solutions to colleagues at all levels within the organization.
* Strategy: develop, align and execute analytical project team plans and strategies to support drug substance and drug product development including methods development, stability and validation activities.
* Laboratory expertise: apply advanced analytical skills and understanding in laboratory techniques routinely used in the analysis of drug substance and drug product samples.
* Collaboration: work both independently and collaboratively within a matrix team environment.
* Communication: demonstrated ability to effectively present results in both oral and written reports and to productively disseminate ideas across discipline and project boundaries.
* Advanced strategic initiatives: develop, contribute and support new ways of working, operating models and paradigms that improve productivity, efficiency and overall effectiveness of workflows and processes.
Knowledge and skills:
* Experienced Analytical Lead (pre-clinical to Phase 1) in the pharmaceutical or biotechnology industry.
* The ability to work successfully in both a team/matrix environment as well as independently.
* Strong understanding of organic reactions and mechanisms.
* Significant experience in achiral and chiral LC method development.
* Technical expertise in analytical techniques that include LC, GC, KF, NMR, XRF, etc.
* Advanced troubleshooting skills and problem-solving capabilities.
* Strong analytical data assessment, review and interpretation skills.
* Advanced experience in communication of technical data: writing reports and presentation skills.
* High attention to detail.
* Ability to work in a fast-paced environment, managing priorities and maintaining timelines.
* Strong knowledge of cGMPs and pharmaceutically relevant regulatory guidelines.
Education and experience:
* Ph.D. with 2-4 years, Master’s degree with 5+ years, or Bachelor’s degree with 8+ years of relevant professional analytical development experience in the pharmaceutical industry.
Flex Designation:
On-Site Designated
Flex Eligibility Status:
In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
#J-18808-Ljbffr