Job summary The Imperial College Healthcare NHS Trust's Hepatology Clinical Research Facility (CRF) for clinical research and investigation is based on the 10th Floor of the Queen Elizabeth Queen Mother Wing at St Mary's Campus and provides a state of the art, designated area for hepatology academics and hepatology clinicians to perform clinical research projects involving both patients with liver conditions and healthy volunteers. The post will specifically help Principal Investigators and the research nursing team with patient recruitment into commercially sponsored clinical drug trials (alcohol, hepatitis, and fatty liver) and the ongoing management of patients according to the study protocols. In undertaking this role, the Clinical Research Fellow will gain experience in the management of clinical trials and novel therapeutics in chronic liver disease. The post is initially for 6 months, but will be renewable, and is suitable for a junior grade doctor (FY2 - FY5) who has a minimum of 1 year's post registration, recent experience of working in the NHS in a medical post, and who is looking to learn and develop clinical research skills. GMC registration and licence to practice are essential. Main duties of the job Support the timely delivery of clinical studies, in-line with the requirements of sponsors, GCP (Good Clinical Practice), and other appropriate guidelines and regulations Provide medical assessment and cover for selected studies in the Hepatology CRF working alongside other clinical teams Perform clinical procedures as appropriate to the assigned study (including, but not limited to, clinical examinations or testing, insertion of intravenous lines, assessment of adverse events and management of medical emergencies) Ensure that patients/volunteers in assigned studies give fully informed consent in writing before commencing a study Assess and interpret safety and clinical data from assigned studies, e.g. vital signs, ECG's, laboratory tests, adverse events etc. Follow up and report Adverse Events as necessary. Communicate safety issues to the Principal Investigator, report Serious Adverse Events in accordance with Good Clinical Practice Ensure that all clinical activities within the CRF are conducted in accordance with approved Standard Operating Procedures (SOPs) Attend clinics and provide clinical cross cover where appropriate Be responsible for specific study-related medical decisions as agreed with the Principal Investigators Assess the eligibility of patient referrals for trials, and maintain and update a screening list About us At Imperial College Healthcare you can achieve extraordinary things with extraordinary people, working with leading clinicians pushing boundaries in patient care. Become part of a vibrant team living our values - expert, kind, collaborative and aspirational. You'll get an experience like no other and will fast forward your career. Benefits include career development, flexible working and wellbeing, staff recognition scheme. Make use of optional benefits including Cycle to work, car lease schemes, season ticket loan or membership options for onsite leisure facilities. The statutory requirement to be fully Covid-19 vaccinated as a condition of employment from April 2022 is subject to legislative review. At Imperial College Healthcare NHS Trust, we strongly encourage and support vaccination uptake as this remains the best line of defence against COVID19. The successful applicant may have contact with patients and service users and as part of our pre-employment checks and risk assessments, we will ask all candidates to confirm whether or not they have been fully vaccinated or have a medical exemption. As part of our continued response to Covid19 we are still conducting the majority of our interviews virtually. We are committed to equal opportunities and improving the working lives of our staff and will consider applications to work flexibly, part-time or job share. Please talk to us at interview. Date posted 05 November 2024 Pay scheme Hospital medical and dental staff Grade Doctor - other Salary Depending on experience £41,750 - £64,288 per annum plus London Weighting Contract Fixed term Duration 6 months Working pattern Full-time Reference number 290-TDPA-195 Job locations St Mary's Hospital London W2 1NY Job description Job responsibilities The postholder will work closely with members of the Hepatology Research team to deliver expert clinical research. They will: Support the delivery of clinical studies, in-line with requirements of sponsors, GCP (Good Clinical Practice), and other appropriate regulations Provide medical assessment and cover for studies in the Hepatology CRF Perform clinical trial procedures (clinical examinations, insertion of intravenous lines, assessment of adverse events and management of medical emergencies, etc) Ensure patients give full informed consent before starting a study Assess and interpret safety and clinical trial data (vital signs, ECG's, laboratory tests, AEs etc). Follow up and report AEs. Communicate safety issues to the Principal Investigator, report SAEs in accordance with Good Clinical Practice Attend clinics and provide clinical cross cover where appropriate Be responsible for specific study-related medical decisions as agreed with the Principal Investigator Assess the eligibility of patients for trials, maintain and update screening lists Accept delegated responsibility to ensure that trials in the Hepatology CRF are carried out safely and in compliance with the protocol Evaluate and manage chronic adverse drug reactions and manage acute toxicological emergencies under the supervision of the consultants in charge Maintain accurate and accessible research records and medical notes Participate in research meetings, study review meetings and meetings with Principal Investigators and study sponsors Any other duties as may be deemed reasonable by senior clinical staff of the Hepatology CRF Job description Job responsibilities The postholder will work closely with members of the Hepatology Research team to deliver expert clinical research. They will: Support the delivery of clinical studies, in-line with requirements of sponsors, GCP (Good Clinical Practice), and other appropriate regulations Provide medical assessment and cover for studies in the Hepatology CRF Perform clinical trial procedures (clinical examinations, insertion of intravenous lines, assessment of adverse events and management of medical emergencies, etc) Ensure patients give full informed consent before starting a study Assess and interpret safety and clinical trial data (vital signs, ECG's, laboratory tests, AEs etc). Follow up and report AEs. Communicate safety issues to the Principal Investigator, report SAEs in accordance with Good Clinical Practice Attend clinics and provide clinical cross cover where appropriate Be responsible for specific study-related medical decisions as agreed with the Principal Investigator Assess the eligibility of patients for trials, maintain and update screening lists Accept delegated responsibility to ensure that trials in the Hepatology CRF are carried out safely and in compliance with the protocol Evaluate and manage chronic adverse drug reactions and manage acute toxicological emergencies under the supervision of the consultants in charge Maintain accurate and accessible research records and medical notes Participate in research meetings, study review meetings and meetings with Principal Investigators and study sponsors Any other duties as may be deemed reasonable by senior clinical staff of the Hepatology CRF Person Specification Education/ qualifications Essential MBBS or equivalent full valid GMC Registration with a licence to practise Desirable Postgraduate specialist qualification e.g. MRCP or equivalent Clinical skills Essential Appropriate to job description Relevant experience in specialty/Sub-specialty Essential 1 year's post- registration recent experience in the NHS in a medical or surgical post Physical examination ECG, chest X ray, other radiology interpretation, biochemistry, haematology results interpretation Venipuncture, IV lines Ability to learn and implement new study related clinical skills Desirable Hepatology clinical experience Audit Essential Knowledge of NHS processes and pressures Experience of teaching students and junior medical staff Understanding of principles of clinical audit Desirable Clinical service development and research experience Previous experience of audit Language Essential Able to speak and write English to the appropriate standard necessary to fulfill the job requirements Person Specification Education/ qualifications Essential MBBS or equivalent full valid GMC Registration with a licence to practise Desirable Postgraduate specialist qualification e.g. MRCP or equivalent Clinical skills Essential Appropriate to job description Relevant experience in specialty/Sub-specialty Essential 1 year's post- registration recent experience in the NHS in a medical or surgical post Physical examination ECG, chest X ray, other radiology interpretation, biochemistry, haematology results interpretation Venipuncture, IV lines Ability to learn and implement new study related clinical skills Desirable Hepatology clinical experience Audit Essential Knowledge of NHS processes and pressures Experience of teaching students and junior medical staff Understanding of principles of clinical audit Desirable Clinical service development and research experience Previous experience of audit Language Essential Able to speak and write English to the appropriate standard necessary to fulfill the job requirements Disclosure and Barring Service Check This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions. Certificate of Sponsorship Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab). From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab). UK Registration Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window). Additional information Disclosure and Barring Service Check This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions. Certificate of Sponsorship Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab). From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab). UK Registration Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window). Employer details Employer name Imperial College Healthcare NHS Trust Address St Mary's Hospital London W2 1NY Employer's website https://www.imperial.nhs.uk/ (Opens in a new tab)