Short summary
An exciting Senior Bioinformatician post is available for MANIFEST (“Multiomic ANalysis of Immunotherapy Features Evidencing Success and Toxicity”), a newly formed ambitious multi-stakeholder consortium involving academic, industry and NHS partners to deliver deep multiomic profiling for patients with cancer undergoing immunotherapy. The MANIFEST consortium represents a diverse group of UK-wide experts in cancer research and clinical care comprising major NHS trusts, academic institutes and universities, and industry partners. This grant is funded by the UK Office of Life Sciences and the Medical Research Council
The post-holder will work under the supervision of Prof. Samra Turajlic (Francis Crick Institute) to quantify dynamic changes in cellular populations as tumours evolve over space and time from primary through to metastatic disease. The primary duty of the post-holder will be to optimise existing algorithms for the analysis and interpretation of multiplex immunofluorescence imaging data, including cell segmentation and quantification and identification of individual cell types within the tumour microenvironment as well as their spatial and social organisation.
Key Responsibilities
Include but not limited to:
• To work within the bioinformatics team of the Turajlic lab, and collaborating groups at Francis Crick Institute and beyond, including academic and industry partners.
• To optimise image analysis platforms capable of answering research questions associated with the response to cancer immunotherapy. To provide expert analysis of high-throughput spatial imaging and spatial omics data.
• To develop and/or optimise methodologies and techniques to address analysis challenges and implement tools, pipelines and data resources in relation to these technologies.
• To provide consultation and communication in data analysis, data mining, and statistics for analysis of biological data.
• To analyse large-scale multi-region imaging data.
• To provide statistical support to other team members.
• To liaise and coordinate between project collaborators
Find out what benefits the Crick has to offer:
For more information on our great pay and benefits package please click here:
Equality, Diversity & Inclusion:
We welcome applications from all backgrounds. We are committed to providing equal employment opportunities, regardless of ethnicity, nationality, gender, sexual orientation, gender identity, religion, pregnancy, age, disability, or civil partnership, marital or family status. We particularly welcome applications from people who are Minority Ethnic as they are currently underrepresented in the Crick at this level.
Diversity is essential to excellence in scientific endeavour. It increases breadth and perspective, leading to more innovation and creativity. We want the Crick to be a place where everyone feels valued and where diversity is celebrated and seen as part of the foundation for our Institute’s success.
The Crick is committed to creating equality of opportunity and promoting diversity and inclusivity. We all share in the responsibility to actively promote dignity, respect, inclusivity and equal treatment and it is our aim to ensure that these principles are reflected and implemented in all strategies, policies and practices.
Read more on our website: