Ready to shape the future of drug discovery?
About Us
Axiom Therapeutics is a growing techbio start-up located in London, UK, developing cutting-edge AI for drug discovery and backed by top EU and US deeptech VCs. Our mission is to design small molecule drugs for the hardest-to-treat human diseases.
Responsibilities
1. Lead and manage multiple complex scientific projects to drive forward Axioms goals.
2. Design and build quantum chemistry pipelines to evaluate small molecule drugs and proteins.
3. Create new quantum chemistry datasets for ML training.
4. Work closely with our ML and biomolecular scientists to integrate their latest advances into Axioms simulation platform.
5. Be part of an interdisciplinary computational team advancing AI+physics in small molecule drug discovery.
Requirements
1. PhD/Postdoc in computational/theoretical chemistry, molecular physics/engineering (or related field) OR M.S + 3 years experience in computational drug discovery.
2. Published track record in method development or application of quantum mechanical (QM) methods including density-functional theory (DFT), force-field development, reaction path/transition state optimisation, QM/MM.
3. Proficiency in using and developing electronic structures codes (VASP, Psi4, PySCF or similar).
4. Proficiency with curating and optimising QM (DFT) datasets.
5. Proficiency in scientific software development in Python.
6. Ability to clearly communicate complex scientific concepts in English.
7. Proven ability to work with interdisciplinary teams.
Desirable
1. Expertise in using QM methods for reaction path optimisation in biomolecules.
2. Familiarity with ML techniques for 3D atomic systems.
3. Familiarity with using machine-learned potential energy surfaces.
4. Proficiency in running distributed compute (CPU/GPU) on clusters/cloud.
5. Familiarity with modern scientific software practices (version control, containerisation, continuous integration etc) and an enthusiasm for writing clear, performant code.
6. Previous work in computational drug discovery in industry.
If you do not quite fulfil all of the requirements or are not sure which of our open roles is right for you then don’t worry, apply anyway.
Position type
1. Full-time role in Marylebone, London, with a hybrid schedule (majority in-office weekly).
2. Starting ASAP.
Benefits
1. Competitive salary and meaningful equity.
2. Key contributor: set the direction of Axiom’s computational research from Day 1.
3. Contribute to cutting-edge computational and chemical research.
4. More benefits as we grow — with the ability to influence which benefits are added.
Ready to apply?
We review applications on a rolling basis, so apply today and join us in transforming the future of small molecule drug discovery!
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