Research Assistant/Associate - Regulation of gene expression
Newcastle University
Newcastle upon Tyne
GBP 40,000 - 60,000
Research Assistant/Associate - Regulation of Gene Expression
Requisition ID: 27802
Location: Newcastle, GB
Contract Type: Fixed Term
Working Pattern: Full Time
Salary: Research Assistant £32,296 to £33,882 per annum; Research Associate £34,866 per annum
Newcastle University is a great place to work, with excellent benefits including a generous holiday package, pension schemes, and health and wellbeing initiatives.
Closing Date: 05 January 2025
The Role
This post is an exciting opportunity for a Research Assistant/Associate to work on a project investigating the molecular mechanisms of cardiovascular disease during prostate cancer therapy. The project is funded by the JGW Patterson Foundation and aims to generate pilot data to support further funding applications.
We are looking for a motivated researcher to perform transcriptomics and functional assays in human cardiomyocytes treated with prostate cancer hormone therapy drugs. You will work with a collaborative team of RNA biologists and cancer researchers based in Newcastle, Leeds, and Sheffield.
This project will provide an opportunity to develop skills in cellular and molecular biology and gain knowledge in a multidisciplinary research area, with the possibility to learn basic bioinformatics skills on your own data.
What do we need from you?
To apply for the position, provide your CV and a covering letter outlining your suitability for the role using examples to highlight how you meet the essential criteria in knowledge, skills, and experience as listed in the job description. Focus your cover letter on the following key areas:
* Regulation of gene expression, especially RNA transcription and processing
* Molecular biology techniques such as nucleic acid extraction, PCR-based methods, and Western blotting
* Mammalian cell culture (including drug treatment and nucleic acid transfection)
* Leading the experimental planning and coordination of a laboratory-based research project
This post is fixed term for 12 months. If successful, you will require a DBS and medical clearance before commencing the role.
Key Accountabilities
* Contribute ideas to enhance technical or methodological aspects of studies
* Develop and carry out the specified project using appropriate techniques
* Determine appropriate methodologies for research
* Contribute to grant applications and develop own research proposals
* Write proposals for individual research funding or contribute to collective bids
* Assess research findings for further investigations
* Write up research for publication and dissemination
* Present research findings at conferences or through publications
* Supervise final year undergraduate research projects with guidance
* Work with support staff and students, interacting with academic members
* Contribute to public engagement events
* Develop awareness of University structures and relevant issues
* Conduct literature reviews relevant to the project
* Manage laboratory consumables and ensure compliance with safety protocols
* Maintain excellent laboratory records of experimental procedures
* Participate fully as a member of the research group
The Person
Knowledge, Skills, and Experience
* Ability to work well as part of a team and acquire new skills
* Subject knowledge of transcription and RNA processing
* Advanced skills related to the research projects
* High analytical and problem-solving capability
* Ability to communicate complex information clearly
* Experience of research with transferable skills
* Presentations at conferences and/or publications
* Laboratory experience in cell and molecular biology techniques
* Ability to formulate hypotheses and develop contingency plans
* Ability to critically interpret data and troubleshoot challenges
* Understanding of laboratory safety protocols
* Adaptability to changing project needs and willingness to learn
* Knowledge of cancer biology and/or cardiovascular biology
Attributes and Behaviour
* Professional attitude and ability to work independently and in a team
* Ability to prioritise key tasks
* Commitment to research integrity and ethical guidelines
* Good interpersonal skills and ability to promote mutual respect
* Flexibility in coordinating use of communal equipment
Qualifications
* Good honours degree in life/biomedical science with subject knowledge in transcription and RNA sequencing (Research Assistant)
* A PhD in life/biomedical sciences, ideally in cancer, vascular, or nuclear biology (Research Associate)
Newcastle University is committed to inclusivity and diversity, actively recruiting from all sectors of society. We are a proud equal opportunities employer.
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