We seek a postdoctoral scientist to work with Professor Sir Shankar Balasubramanian on the chemical biology of nucleic acids and their role in the fundamental mechanisms of cancer. The post will be based in our group at Cancer Research UK's Cambridge Institute (CI) and involves close collaboration with our group based in the University Chemistry Department. The post is available immediately.
We have a vacancy for a molecular biologist to contribute to our research on genome structure and function. Current projects include elucidating four-stranded nucleic acid structures (G-quadruplexes), their interacting proteins, their mechanisms in relation to gene expression regulation, and their suitability as therapeutic targets and biomarkers of cancer. We also study the structure and function of chemically-modified DNA bases and their epigenetic roles in normal biology and disease. Our interdisciplinary lab innovates and applies methods that include sequencing technologies, genome-targeting, and chemical biology.
Our ideal candidate will have a capacity for innovation, initiative, and creativity to solve biological problems using molecular and cellular strategies. We value good communication skills and an ability to work well in a multi-disciplinary team. This project provides an opportunity for an outstanding individual to make an inspired contribution to the fundamental understanding of genome function.
Candidates should have (or be about to receive) a PhD in a relevant discipline. For queries regarding this post, please contact Jo Lockhart, Science Administrator, Balasubramanian Group, email: BalasubramanianRecruitment@ch.cam.ac.uk.
Fixed-term: The funds for this post are available for 2 years in the first instance. Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) check and a security check.
Please ensure that you upload a 2-page Curriculum Vitae (CV), a covering letter, and a publications list in the Upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application.
Please quote reference SW45402 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity, and inclusion and encourages applications from all sections of society. The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
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