4basebio is an innovative gene synthesis company with the ambition to provide high quality, synthetic DNA for use in gene therapy and gene editing platforms. We are expanding our MSAT team at our site just north of Cambridge, UK to facilitate the purification of synthetic DNA products for use in AAV, IVT mRNA processes and other therapeutic areas. We are looking for dynamic and experienced team members to help us achieve our ambitions and goals.
The role will support the development, optimisation and validation of new products within the company. In addition, there will be opportunity for the candidate to interact with multi-disciplinary teams within the Research department and expand their laboratory skill set.
Job Responsibilities :
* Work to support the development and optimisation of new products to ensure successful manufacture
* Perform various QC analysis experiments using 4bb DNA and RNA including:
1. Restriction digests & other Molecular techniques
2. CGE methods
3. Sequencing
4. Protein quantification assays
* Support the fill and finish of 4bb products
* Work collaboratively to support the R&D and manufacturing functions of the Company
* Record experimental methods and results to a high standard and in-line with company guidelines
* Attend and participate in relevant meetings, training, and development sessions
* Use, maintain and respect company equipment in accordance with the company’s SOPs and health & safety guidelines
* Undertake any other appropriate roles and responsibilities that reasonably fall within the role holder’s skills and experience as requested
* Be prepared to travel to other 4basebio sites
Person Specification:
* Relevant laboratory experience is required
* Knowledge and some practical experience in capillary gel electrophoresis & protein quantification techniques
* Knowledge and practical experience of molecular biology techniques including gel electrophoresis, DNA handling and quantification is required
* Excellent pipetting techniques
* Excellent team working and communication skills
* Excellent record keeping skills & attention to detail
* Must hold the right to work in the UK (we are unable to offer continued visa sponsorship for this role)
What we offer:
Competitive salary + comprehensive benefits package
If you are interested in joining the 4basebio team, please forward your CV to HR@4basebio.com
Due to the high number of applicants, if you do not hear back from us within six weeks, we thank you for your interest, but please assume you have not been selected for interview on this occasion.