Job Description Our Human Disease Modelling group is seeking an innovative and dynamic Senior Research Scientist to play an important role in expanding our capabilities at the Oxford Research site. The successful candidate will help us utilize a range of technologies to test therapeutic hypotheses, discover novel target biology, characterize potential drug candidates and develop translational biomarkers. This position will involve working in close collaboration with other researchers and across drug discovery disciplines to ensure that we deliver medicines that treat the underlying cause of serious diseases. General Summary: The Molecular Cell and Biology Senior Research Scientist is responsible for experimental productivity and emerging creativity and versatility. The Senior Research Scientist designs and executes experiments for major research projects in the relevant areas of disease biology using patient-relevant cellular models and appropriate readouts of the disease or target mechanisms under investigation. Demonstrates resourcefulness in running multiple activities concurrently, all related to achievement of goals/ objectives. Adapts to new projects rapidly and to multiple projects effectively ensuring alignment with corporate goals. The Senior Research Scientist commands a deep understand of specialized discipline(s) and possesses diverse project experience and a broad panorama of (relevant) literature familiarity. Key Duties and Responsibilities: Designs and performs technically challenging experiments Distills complicated, multidimensional data to clear hypotheses and new experimental directions Prioritizes own studies within Projects and balances activities across Projects effectively Performs advanced experimental troubleshooting and methods development Innovates on research methodology, in order to address more important questions Scours relevant scientific literature within field and surveys broadly beyond own discipline/field “Imports” new principles/concepts from other fields to develop useful new experimental approaches Education and Experience: Ph.D. (or equivalent degree) in molecular biology, cell biology, biochemistry, or related disciplines and 2-5 years of relevant post-doctoral employment experience Strong cell biology background using a range of human cell systems and assays. Versatile molecular and cell biology experience, ideally including flow cytometry, clonal cell line generation, and luminescence assays. Proven track record for solving complex scientific problems and delivering high quality results, supported by evidence of significant individual contributions Strong verbal and written communication and team working skills Motivated and curious; happy to work across a broad range of biological subjects and projects in order to identify the molecular drivers of disease Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistancevrtx.com