Site Name: UK - Hertfordshire - Stevenage
Posted Date: Oct 22 2024
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. Science and technology are coming together in a way they never have before, and we have strong tech-enabled capabilities that allow us to build a deeper understanding of the patient, human biology and disease mechanisms, and transform medical discovery.
We are seeking a Senior Scientist in Synthetic Chemistry to join our high throughput experimentation team in Molecular Modalities Capabilities (MMC).
This role is for a laboratory-based chemist carrying out experimental work within GSK’s Molecular Modalities Capabilities department. For the successful candidate, this involves deploying medium to ultra high-throughput organic synthesis to generate compounds to test medicinal chemistry hypotheses across a range of modalities, and the development and implementation of new capabilities and technologies to accelerate the drug discovery process and generate high quality reusable data for drug discovery.
This position requires an individual with strong synthetic, technical, analytical and personal skills, and a commitment to further personal development as a scientist.
In this role you will:
* Develop and realise medicinal/synthetic chemistry plans with high scientific rigour.
* Maintain high laboratory productivity to enable significant and high-quality synthetic contribution to the programmes and platform builds with which you are associated.
* Design, implement, analyse and problem solve as appropriate, with minimal supervision.
Role A – Senior Scientist Molecular Modalities Capabilities
* Work across boundaries to develop and implement best-in-class technological platforms targeted at accelerating the generation of high quality, reusable data for drug discovery.
* Stay up to date with the latest advancements in chemistry and technologies aligned to the group remit and evaluate their potential applications in the discovery of novel therapeutics.
Role B – Senior Scientist Discovery Chemistry
* Develop and implement strategies for efficient and high-quality synthesis, purification, and characterisation of antibody drug conjugates.
* Carry out experimental work within the Discovery Chemistry group, designing and executing synthetic plans to deliver antibody drug conjugates for biological evaluation.
Basic Qualifications & Skills:
* Chemistry (or equivalent) degree with strong academic performance.
* The equivalent experience in a professional industrial setting or a PhD/DPhil (or about to be awarded a PhD/DPhil) in synthetic chemistry/medicinal chemistry/chemical biology/antibody drug conjugates.
* Ability to understand, interpret and communicate complex scientific data.
* Excellent written and oral communication skills enabling efficient presentation of scientific findings to both technical and non-technical audiences.
Preferred Qualifications & Skills:
Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:
* Experience and/or knowledge of the use of novel technologies in modern organic synthesis.
* An awareness and understanding of medicinal chemistry principles within a drug discovery setting.
* Experience with laboratory automation and the development of automation workflows.
* Experience with data analytics platforms and coding.
Closing Date for Applications – Monday 4th November
When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above.
Why GSK?
GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people.
As an Equal Opportunity Employer, we are open to all talent. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.
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