4,000 professionals, 0 days wasted, 1 incredible purpose. Together, we are beating cancer.
Senior Scientist (Biophysics and/or Biochemistry)
Starting salary: From £41,700-£46,500 per annum depending on experience plus benefits
Reports to: Principal Scientist, Mechanistic Pharmacology
Department: Research and Innovation
Contract: Permanent
Hours: Full time 35 hours per week (flexible working requests considered if they meet business needs)
Location: Babraham Research Campus, Cambridge or Scotland Institute, Glasgow
Closing date: 16 February 2025 23:55. This vacancy may close earlier if a high number of applications are received or once a suitable candidate is found, so please do not delay submitting your application to avoid any disappointment.
Visa sponsorship: Cancer Research UK can consider visa sponsorship for this vacancy. If this applies to you, please ensure that this is clearly marked on your application.
At Cancer Research UK, we exist to beat cancer.
We are professionals with purpose, beating cancer every day. But we need to go much further and much faster. That’s why we’re looking for someone talented, someone determined, someone like you.
We currently have an opportunity within our Drug Discovery team for an experienced and passionate Senior Scientist to bring scientific excellence and expertise to the design, prosecution and analysis of biochemical and/or biophysical assays including bespoke mechanistic data and compound profiling.
About CRUK Drug Discovery
As the world’s biggest medical research charity, we have helped bring eleven new cancer drugs to market. However, there is still an urgent need to bring more effective treatments to patients faster.
We have recently developed a new approach to driving therapeutic innovation through the creation of Cancer Research Horizons (CRH). We have brought together Cancer Research UK’s established drug discovery teams under one organisation and leadership team, combining our unique pipeline of world class biology, cutting edge technology platforms and clinical expertise to 1) bring new treatments to patients faster and 2) tackle the biggest challenges in discovering cancer drugs by seeking out more radical ideas and embracing risk in our bid to achieve success.
What will I be doing?
This laboratory-based role is focussed on designing and developing physiologically relevant biochemical and/or biophysical assays to characterise cancer targets in detail at the molecular level, enable high-throughput screening, profile the structure-activity and structure-kinetic relationships of small molecules, and characterise their mechanism of action to inform dose prediction and clinical efficacy.
The successful candidate will drive innovative ways of working through keeping abreast of cutting-edge biochemistry, enzymology and biophysics. They will form an integral part of the Cancer Research Horizon Drug Discovery team working alongside our industry and academic partners to progress novel cancer targets towards patient benefit.
What skills will I need?
1. A BSs, MSc or PhD in biological science such as biochemistry or pharmacology; relevant experience may be substituted for education.
2. Significant experience in a drug discovery environment of assay development and dissecting enzyme and small molecule inhibitor mechanisms for a range of target classes.
3. Detailed theoretical and practical understanding of biochemical and/or biophysical assays and detection technologies, with a particular focus on physiologically relevant systems.
4. Experience in liquid handling and automated dispensing will be an advantage.
5. Experience of the use of packages such as Kintek to model and simulate assay data will be an advantage.
What will I gain?
Our organisation values are designed to guide all that we do.
Bold: Act with ambition, courage and determination.
Credible: Act with rigour and professionalism.
Human: Act to have a positive impact on people.
Together: Act inclusively and collaboratively.
We’re looking for people who can believe in and embody these organisation values and can use them to drive forward progress against our mission to beat cancer.
If you’re interested in applying and excited about working with us but are unsure if you have the right skills and experience we’d still love to hear from you.
We create a working environment that supports your wellbeing and provide a generous benefits package, a wide range of career and personal development opportunities and high-quality tools. Our policies and processes enable you to improve your work-life balance, take positive steps in your career and achieve your personal wellbeing goals.
You can explore our benefits by visiting our careers web page.
How do I apply?
We operate an anonymised shortlisting process in our commitment to equality, diversity and inclusion. CVs are required for all applications; but we won’t be able to view them until we invite you for an interview. Instead, we ask you to complete the work history section of the online application form for us to be able to assess you fairly and objectively.
One of our values at CRUK is Being Human. Whilst we understand that AI has its benefits, we want to hear about your personal experiences and why these make you suitable for the role. We have noticed some applicants being less successful in their applications when using AI due to lack of real life examples. To level the playing field and ensure fairness for all candidates, we strongly encourage responses to be written in your own words, drawing from personal experiences and knowledge. We discourage the use of AI when completing your application form and throughout the process.
For more information on this career opportunity please visit our website or contact us at recruitment@cancer.org.uk.
For more updates on our work and careers, follow us on: Linked In, Facebook, Instagram, X and YouTube.
Our vision is to create a charity where everyone feels like they belong, benefits from and participates in, the work we do. We actively encourage applications from people of all backgrounds and cultures, in particular those from ethnic minority backgrounds who are currently under-represented.
We want to see every candidate performing at their best throughout the job application process, interview process and whilst at work. We therefore ask you to inform us of any concerns you have or any adjustments you might need to enable this to happen. Please contact recruitment@cancer.org.uk or 020 3469 8400 as soon as possible.
Unfortunately, we are unable to recruit anyone below the age of 18, so that we can protect young people from health & safety and safeguarding risks.
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